A Facile One-Pot Method for Synthesis of 2,4-Dichloroquinoline Derivatives

Authors

  • Hassan Kefayati Department of Chemistry, Faculty of Sciences, Shahid Beheshty University, Tehran, I.R. IRAN
  • Javad Azizian Department of Chemistry, Faculty of Sciences, Shahid Beheshty University, Tehran, I.R. IRAN
  • Khosrow Jadidi Department of Chemistry, Faculty of Sciences, Shahid Beheshty University, Tehran, I.R. IRAN
  • Morteza Mehrdad Department of Chemistry, Faculty of Sciences, Shahid Beheshty University, Tehran, I.R. IRAN
  • Yaghob Sarrafi Department of Chemistry, Faculty of Sciences, Shahid Beheshty University, Tehran, I.R. IRAN
Abstract:

A facile one-pot method with good yield for the synthesis of 2,4-dichloroquinoline and some related new derivatives by condensation of the appropriate primary aromatic amine with malonic acid in presence of excess phosphorus oxychloride is described.  

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Journal title

volume 20  issue 1

pages  20- 21

publication date 2001-06-01

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